BDBM214799 1xx

SMILES FC(F)(F)c1cc(NC(=O)[C@H]2CC=C[C@H]3CCN(Cc4ccccc4)C(=O)[C@@H]23)ccc1Cl

InChI Key InChIKey=BSPPZJZWKVYWNH-DJPFJPOOSA-N

Data  27 KI  26 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 214799   

TargetKappa-type opioid receptor [K200A](Homo sapiens (Human))
University of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataKi:  180nM ΔG°:  -9.19kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [K200A](Homo sapiens (Human))
University of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  80nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed